Flight Heathrow Airport departs from London Heathrow Airport at 16:35 and arrives at Madrid Adolfo Suárez Madrid–Barajas Airport at 19:55.
The flighttime is about 2h 20m. The distance travelled ("as the bird flies"): 1268 Km. So the average speed is roughly 543 Km.
There is an 1 hour time difference between London and Madrid