Flight Václav Havel Airport Prague departs from Prague Václav Havel Airport Prague at 12:15 and arrives at Moscow Sheremetyevo International Airport at 16:50.
The flighttime is about 3h 35m. The distance travelled ("as the bird flies"): 2639 Km. So the average speed is roughly 736 Km.
There is an 1 hour time difference between Prague and Moscow