Flight George Bush Intercontinental Airport departs from Houston George Bush Intercontinental Airport at 22:05 and arrives at Santiago Arturo Merino Benitez International Airport at 10:20.
The flighttime is about 10h 15m. The distance travelled ("as the bird flies"): 2458 Km. So the average speed is roughly 240 Km.
There is an 2 hour time difference between Houston and Santiago