Please be aware that Melbourne has multiple airports and that these results are for all airports serving the city.
The best month to fly between Melbourne and Brisbane is January and the most expensive month to fly is October. (Average prices, based on 459 datapoints.)
The best day to arrive at Melbourne is Friday and it would be best to avoid Sunday, as prices are on average 76.13% higher than on Friday. (Average prices, based on 2860 datapoints.)
The cheapest airline flying from Melbourne to Brisbane is JetStar Airways. They are 44% cheaper than Qantas. (Average prices, based on 478 datapoints.)
The best time to fly is at around 21. (Average prices, based on 829 datapoints.)